Reply.ioAI Sales Outreach & Cold Email Platform
vs
TwentyThe #1 Open Source CRM for modern teams.
Comparison · Sales Engagement · weekly run Nov 3
Reply.io vs Twenty
Which one do AI engines recommend, and how do they differ on price, fit and features?
The short answer
Reply.io is the stronger AI pick in Sales Engagement: it has a visibility score of 14.4 versus 0 for Twenty.
Choose Reply.io if…
- You want the brand AI engines rank higher (14.4 vs 0)
- You need SOC 2 or GDPR coverage
- You prefer a larger, established vendor (51–200 employees)
- Flat tiers pricing suits your budget better than per seat
Choose Twenty if…
- You want a free plan to start
- You need SOC 2 Type II coverage
- Per seat pricing suits your budget better than flat tiers
AI visibility side by side
Latest weekly run · Nov 3
| Metric | Reply.io | Twenty |
|---|---|---|
| Visibility score | 14.4% | 0% |
| Change vs last week | down−3.3% | no change0% |
| Rank in Sales Engagement | #6 | #58 |
| Share of voice | 3.5% | 0% |
| Mentions this run | 23 | 0 |
| Positive in AI answers | 42% | — |
The stronger value in each row is marked with a ✓.
Visibility score trend
Weekly runs over the last 60 days
Reply.io −3.299999999999999pp · Twenty 0pp over 1 weekly runs.
Engine by engine
Reply.io leads on 3 of 3 engines
ChatGPT
AI Mode
Perplexity
Reply.ioTwenty
Head to head in AI answers
0 engine answers name both brands
0Reply.io ranked higher
0Twenty ranked higher
Features, pricing & fit
| Dimension | Reply.io | Twenty |
|---|---|---|
| Pricing model | Flat tiers | Per seat |
| Entry price | $49 / mo | Free; paid from $9 per seat / mo |
| Free plan | No · 14-day trial | Yes |
| Deployment | — | Self-hosted or managed cloud |
| Compliance | SOC 2, GDPR | SOC 2 Type II |
| Support | Live chat, Email, CSM onboarding | Community, Email and chat, Priority support, Dedicated support and SLA |
| Founded | 2014 | 2023 |
| Headquarters | San Jose, California, US | San Francisco, California, United States |
| Employees | 51–200 | 1–10 |
| Funding | Series A | Series B · $105M raised |
| Best for | Founders, sales teams, and agencies who need results fast without juggling 5+ tools. | Technical teams that want a custom CRM they can own, extend with code and adapt as the business grows. |
Plans side by side
Reply.io
Email Volume$49month, billed annually (1,000 active contacts; monthly $59)
Multichannel$89user/month, billed annually (monthly $99)
AI SDR Starter$500month, billed annually (1,000 active contacts; monthly $800)
AI SDR Growth$1,500month, billed annually (5,000 active contacts; monthly $2500)
AI SDR EnterpriseCustomcontact us
Agency Core$210month
Agency AI SDR$500month/client
Pros and cons
Themes from the AI answers that mention each brand
Reply.io
- Multichannel outreach and AI-assisted engagement across email, calls, LinkedIn and more
- 14-day free trial to test core sequencing and automation
- Transparent self-serve pricing with annual discounts
- Affordable, lower-cost option
- Strong choice for smaller and mid-market sales teams
Twenty
Profile in progress.
Data collected ·ChatGPT, Perplexity, Google AI Mode·coverage 98.8%·next run
Cite as: SlateIndex, “Reply.io vs Twenty”, https://slateindex.ai/compare/reply-io-vs-twenty, data of Nov 3, 2026. Licence: CC BY 4.0.