Reply.ioAI Sales Outreach & Cold Email Platform
vs
ZendeskAI-powered customer service platform
Comparison · Sales Engagement · weekly run Nov 3
Reply.io vs Zendesk
Which one do AI engines recommend, and how do they differ on price, fit and features?
The short answer
Reply.io is the stronger AI pick in Sales Engagement: it has a visibility score of 14.4 versus 0.4 for Zendesk.
Choose Reply.io if…
- You want the brand AI engines rank higher (14.4 vs 0.4)
- AI answers describe it more positively (42% vs 34% positive)
- You need SOC 2 or GDPR coverage
- Flat tiers pricing suits your budget better than per seat
Choose Zendesk if…
- You want a lower entry price ($19 vs $49)
- You need SOC 2 Type II or ISO 27001:2022 or ISO 27018:2019 or ISO 27701:2019 or ISO 27017:2015 or ISO 42001:2023 or FedRAMP LI-SaaS or Cyber Essentials Plus coverage
- You prefer a larger, established vendor (5,000+ employees)
- Per seat pricing suits your budget better than flat tiers
AI visibility side by side
Latest weekly run · Nov 3
| Metric | Reply.io | Zendesk |
|---|---|---|
| Visibility score | 14.4% | 0.4% |
| Change vs last week | down−3.3% | up+0.1% |
| Rank in Sales Engagement | #6 | #40 |
| Share of voice | 3.5% | 0.1% |
| Mentions this run | 23 | 1 |
| Positive in AI answers | 42% | 34% |
The stronger value in each row is marked with a ✓.
Visibility score trend
Weekly runs over the last 60 days
Reply.io −3.299999999999999pp · Zendesk +0.10000000000000003pp over 1 weekly runs.
Engine by engine
Reply.io leads on 3 of 3 engines
ChatGPT
AI Mode
Perplexity
Reply.ioZendesk
Head to head in AI answers
0 engine answers name both brands
0Reply.io ranked higher
0Zendesk ranked higher
Features, pricing & fit
| Dimension | Reply.io | Zendesk |
|---|---|---|
| Pricing model | Flat tiers | Per seat |
| Entry price | $49 / mo | $19 per seat / mo |
| Free plan | No · 14-day trial | No |
| Deployment | — | Cloud (SaaS) |
| Integrations | — | 1800+ |
| Compliance | SOC 2, GDPR | SOC 2 Type II, ISO 27001:2022, ISO 27018:2019, ISO 27701:2019, ISO 27017:2015, ISO 42001:2023, FedRAMP LI-SaaS, Cyber Essentials Plus |
| Support | Live chat, Email, CSM onboarding | Help Center, Community, Partners |
| Founded | 2014 | 2007 |
| Headquarters | San Jose, California, US | San Francisco, California, United States |
| Employees | 51–200 | 5,000+ |
| Funding | Series A | Take-private (Hellman & Friedman, Permira) |
| Best for | Founders, sales teams, and agencies who need results fast without juggling 5+ tools. | Support teams from startups to enterprises that need omnichannel ticketing with AI automation |
Plans side by side
Reply.io
Email Volume$49month, billed annually (1,000 active contacts; monthly $59)
Multichannel$89user/month, billed annually (monthly $99)
AI SDR Starter$500month, billed annually (1,000 active contacts; monthly $800)
AI SDR Growth$1,500month, billed annually (5,000 active contacts; monthly $2500)
AI SDR EnterpriseCustomcontact us
Agency Core$210month
Agency AI SDR$500month/client
Zendesk
Support Team$19agent/month paid yearly
Suite Team$55agent/month paid yearly
Suite Professional$115agent/month paid yearly
Suite Enterprise + CopilotCustomcontact sales
Pros and cons
Themes from the AI answers that mention each brand
Reply.io
- Multichannel outreach and AI-assisted engagement across email, calls, LinkedIn and more
- 14-day free trial to test core sequencing and automation
- Transparent self-serve pricing with annual discounts
- Affordable, lower-cost option
- Strong choice for smaller and mid-market sales teams
Zendesk
- Industry leader in omnichannel customer support
- Scalable platform for large enterprise teams
- Mature ticketing operations and SLA management
- Extensive marketplace and broad integrations
- Free trial available for 14 days
- Heavy, slow deployment compared with lighter tools
- High per-agent costs
- AI add-ons billed separately on top of base fee
Data collected ·ChatGPT, Perplexity, Google AI Mode·coverage 98.8%·next run
Cite as: SlateIndex, “Reply.io vs Zendesk”, https://slateindex.ai/compare/reply-io-vs-zendesk, data of Nov 3, 2026. Licence: CC BY 4.0.