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Reply.ioAI Sales Outreach & Cold Email Platform
vs
ZendeskAI-powered customer service platform
Comparison · Sales Engagement · weekly run Nov 3

Reply.io vs Zendesk

Which one do AI engines recommend, and how do they differ on price, fit and features?

The short answer

Reply.io is the stronger AI pick in Sales Engagement: it has a visibility score of 14.4 versus 0.4 for Zendesk.

Choose Reply.io if…

  • You want the brand AI engines rank higher (14.4 vs 0.4)
  • AI answers describe it more positively (42% vs 34% positive)
  • You need SOC 2 or GDPR coverage
  • Flat tiers pricing suits your budget better than per seat

Choose Zendesk if…

  • You want a lower entry price ($19 vs $49)
  • You need SOC 2 Type II or ISO 27001:2022 or ISO 27018:2019 or ISO 27701:2019 or ISO 27017:2015 or ISO 42001:2023 or FedRAMP LI-SaaS or Cyber Essentials Plus coverage
  • You prefer a larger, established vendor (5,000+ employees)
  • Per seat pricing suits your budget better than flat tiers

AI visibility side by side

Latest weekly run · Nov 3

Metric Reply.io Zendesk
Visibility score14.4%0.4%
Change vs last weekdown−3.3%up+0.1%
Rank in Sales Engagement#6#40
Share of voice3.5%0.1%
Mentions this run231
Positive in AI answers42%34%

The stronger value in each row is marked with a ✓.

Visibility score trend

Weekly runs over the last 60 days

0%25%50%75%100%Nov 2Nov 3Reply.io 14%

Reply.io −3.299999999999999pp · Zendesk +0.10000000000000003pp over 1 weekly runs.

Engine by engine

Reply.io leads on 3 of 3 engines

ChatGPT
24.1%
0%
AI Mode
6.1%
0%
Perplexity
13%
1.1%
Reply.ioZendesk

Head to head in AI answers

0 engine answers name both brands

0Reply.io ranked higher
0Zendesk ranked higher

Features, pricing & fit

DimensionReply.ioZendesk
Pricing modelFlat tiersPer seat
Entry price$49 / mo$19 per seat / mo
Free planNo · 14-day trialNo
Deployment—Cloud (SaaS)
Integrations—1800+
ComplianceSOC 2, GDPRSOC 2 Type II, ISO 27001:2022, ISO 27018:2019, ISO 27701:2019, ISO 27017:2015, ISO 42001:2023, FedRAMP LI-SaaS, Cyber Essentials Plus
SupportLive chat, Email, CSM onboardingHelp Center, Community, Partners
Founded20142007
HeadquartersSan Jose, California, USSan Francisco, California, United States
Employees51–2005,000+
FundingSeries ATake-private (Hellman & Friedman, Permira)
Best forFounders, sales teams, and agencies who need results fast without juggling 5+ tools.Support teams from startups to enterprises that need omnichannel ticketing with AI automation

Plans side by side

Reply.io

Email Volume$49month, billed annually (1,000 active contacts; monthly $59)
Multichannel$89user/month, billed annually (monthly $99)
AI SDR Starter$500month, billed annually (1,000 active contacts; monthly $800)
AI SDR Growth$1,500month, billed annually (5,000 active contacts; monthly $2500)
AI SDR EnterpriseCustomcontact us
Agency Core$210month
Agency AI SDR$500month/client
Reply.io pricing

Zendesk

Support Team$19agent/month paid yearly
Suite Team$55agent/month paid yearly
Suite Professional$115agent/month paid yearly
Suite Enterprise + CopilotCustomcontact sales
Zendesk pricing

Pros and cons

Themes from the AI answers that mention each brand

Reply.io

  • Multichannel outreach and AI-assisted engagement across email, calls, LinkedIn and more
  • 14-day free trial to test core sequencing and automation
  • Transparent self-serve pricing with annual discounts
  • Affordable, lower-cost option
  • Strong choice for smaller and mid-market sales teams

    Zendesk

    • Industry leader in omnichannel customer support
    • Scalable platform for large enterprise teams
    • Mature ticketing operations and SLA management
    • Extensive marketplace and broad integrations
    • Free trial available for 14 days
    • Heavy, slow deployment compared with lighter tools
    • High per-agent costs
    • AI add-ons billed separately on top of base fee

    Data collected ·ChatGPT, Perplexity, Google AI Mode·coverage 98.8%·next run

    Cite as: SlateIndex, “Reply.io vs Zendesk”, https://slateindex.ai/compare/reply-io-vs-zendesk, data of Nov 3, 2026. Licence: CC BY 4.0.